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Heel - a Christian perspective
When God cursed Adam and Eve after the Fall, he also cursed the serpent (Satan) who had tempted them into evil. He promised that while the serpent would wound the Messiah, the serpent would ultimately be destroyed.

http://biblegateway.com/passage/?search=Genesis%203:15&version=NIV

Crush in the Bible - a Christian perspective
God curses the serpent for his role in man's fall. He says that the serpents head will be crushed and he will bite at man's heel.

http://biblegateway.com/passage/?search=Genesis%203:14-15&version=NIV